AIDS-related diffuse large B-cell lymphoma - MRI + CT Scans
Saggital T1-weighted MRI scan. A 34-year-old-male patient. A large plaque in the epidural space surrounding and encroaching on the spinal cord. Left-sided paravertebral and prevertebral soft tissues are edematous but without destruction of the vertebral bodies and ribs. Signal change in the bone marrow of the adjacent thoracic vertebral bodies (Th2-Th3). AIDS positive - AIDS-related diffuse large B-cell lymphoma. Immunohistochemical studies have been performed. The large atypical lymphoid cells are strongly positive for CD20, Pax-5, CD45, CD30 and EBER-ISH. They are negative for EMA, ALK, CD15, CD79a, and Cyclin D1. The Ki-67 proliferative index in the large cells is approximately 95%. The admixed small lymphocytes are reactive T cells (CD3 and CD5 positive) and there are a few admixed macrophages showing a para nuclear dot-like pattern of staining for CD15. The atypical lymphoid population is CD10 negative, BCL-6 positive, and MUM1 positive.
3419 x 4000 pixels
Print Size @ 300 dpi
11 x 13 inches / 29 x 34 cm