Pemphigus
A 12 years old girl with extensive bullous eruption started one month earlier. Clinical exam of the mouth showed erosions and bullae. Dermatopathology: separation of of keratinocytes, suprabasally, leading to split just above the basal cell layer. Direct Immunofluorescence staining reveals IgG and often C3 deposited in lesional and paralesional skin in the intercellular substance of the epidermis. It was a Pemphigus vulgaris. It is a sereious and often fatal disease unless treated with immunosuppressive agents.
Credit
Nejib Doss
Dimensions
2304 x 1536 pixels
Print Size @ 300 dpi
8 x 5 inches / 20 x 13 cm
